Issues for Surgery |
For treatment of angina – exacerbation of symptoms if omitted. |
Advice in the Perioperative period |
Elective and Emergency Surgery Continue. Post-operative Advice Restart post-operatively as soon as next dose is due. |
Interaction(s) with Common Anaesthetic Agents |
None1, 2, 3, 4. |
Interaction(s) with other Common Medicines used in the Perioperative Period |
QT-Interval Prolongation Ranolazine prolongs the QT-interval in a dose-dependent manner3. Concurrent use with other drugs that can prolong the QT-interval might increase the risk. These include1, 2, 3, 4: -
*monitor ECG with concurrent use if risk factors for QT-interval prolongation also present (increasing age, female sex, cardiac disease, and some metabolic disturbances e.g. hypokalaemia) Hypokalaemia Corticosteroids may cause hypokalaemia, potentially increasing the risk of torsades de pointes – monitor serum potassium concentrations1. |
Further Information |
None relevant.
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References |
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