Issues for Surgery
Deterioration in cognitive function if omitted.
Advice in the Perioperative period
Elective and Emergency Surgery
Interaction(s) with Common Anaesthetic Agents
Esketamine and Ketamine
Concurrent use of memantine and esketamine / ketamine should be avoided. Both medicines are N-methyl-D-aspartate (NMDA) antagonists and potentially concurrent use could increase the frequency and severity of central nervous system adverse drug reactions including psychosis1, 2, 3.
Interaction(s) with other Common Medicines used in the Perioperative Period
None1, 2, 3.