Co-magaldrox (Maalox®, Mucogel®), Co-simalcite (Altacite Plus®), Magnesium carbonate, Magnesium trisilicate, Magnesium trisilicate with magnesium carbonate and sodium bicarbonate, Simeticone with aluminium hydroxide and magnesium hydroxide (Maalox Plus®), Sodium alginate with calcium carbonate and sodium bicarbonate (Acidex®, Gaviscon®, Peptac®), Sodium alginate with potassium bicarbonate (Acidex Advance®, Gaviscon Advance®)
Issues for Surgery
Loss of symptomatic relief from dyspepsia and gastro-oesophageal reflux disease (GORD) if omitted.
Advice in the Perioperative period
Elective and Emergency Surgery
Aluminium containing antacids should be used with caution in patients with renal impairment, particularly if also prescribed effervescent medications e.g. soluble paracetamol (see Further Information)1, 2.
For patients on enteral feeds – see Interaction(s) with other Common Medicines used in the Perioperative Period.
Patients Undergoing Anti-Reflux Surgery or Total Gastrectomy
Interaction(s) with Common Anaesthetic Agents
None1, 2, 3, 4, 5, 6.
Interaction(s) with other Common Medicines used in the Perioperative Period
Administration of antacids containing aluminium, calcium or magnesium might damage enteric coatings designed to prevent dissolution in the stomach and can impair absorption of other medications. If administering medication where a reduction in bioavailability could have a clinically significant effect on safety or efficacy (e.g. antimicrobials), administration of the medication should be separated from the antacid, to allow for appropriate absorption1, 4.
Consult product literature for recommendations on separating doses to ensure absorption.
Risk of aluminium toxicity